BR102910 是一种选择性的成纤维细胞活化蛋白 (FAP) 抑制剂，IC50 为 2 nM。BR102910 还抑制脯氨酰寡肽酶 (PREP)，IC50 为 49.00 μM。BR102910可用于2型糖尿病的研究。
货号:ajcx39648
CAS:2505339-54-6
分子式:C18H14Cl2F2N4O2S
分子量：459.3
溶解度:N/A
纯度：98%
存储：Store at -20°C
库存：现货

Background:

BR102910 is a selective fibroblast activation protein (FAP) inhibitor with the IC50 of 2 nM. BR102910 also inhibits prolyl oligopeptidase (PREP) with the IC50 of 49.00 μM. BR102910 can be used for the researchof type 2

BR102910 (C57BL/6J mice, 0-30 mg/kg, Orally, once) shows significant FAP inhibition in a dose dependent manner[1].

[1]. Hui Jin Jung, et al. Identification of BR102910 as a selective fibroblast activation protein (FAP) inhibitor. Bioorg Med Chem Lett. 2021 Apr 1;37:127846.