ABBV-167 是一种 BCL-2 抑制剂 venetoclax 的磷酸盐前药。
货号:ajcx38074
CAS:1351456-78-4
分子式:C46H53ClN7O11PS
分子量:978.45
溶解度:DMSO : 100 mg/mL (102.20 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
ABBV-167 is a phosphate prodrug of the BCL-2 inhibitor venetoclax.
[1]. Salem AH, et al. Expanding the Repertoire for "Large Small Molecules": Prodrug ABBV-167 Efficiently Converts to Venetoclax with Reduced Food Effect in Healthy Volunteers. Mol Cancer Ther. 2021 Jun;20(6):999-1008.