CCT245232 是热激因子 1 (HSF1) 的有效抑制剂。HSF1 是热激反应的主要调节因子，其中多个基因被诱导以响应温度升高和其他压力。CCT245232 具有研究增殖性疾病的潜力，例如癌症 (信息提取自专利 WO2015049535A1)。
货号:ajcx38010
CAS:1693731-14-4
分子式:C27H23N3O4
分子量：453.49
溶解度:DMSO : 41.67 mg/mL (91.89 mM; ultrasonic and warming and heat to 60°C)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

CCT245232 is a potent inhibitor of heat shock factor 1 (HSF1). HSF1 is the master regulator of the heat shock response, in which multiple genes are induced in response to temperature increase and other stresses. CCT245232 has the potential for the research of proliferative diseases, such as cancer (extracted from patent WO2015049535A1)[1].

[1]. Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. Patent WO2015049535A1.