Lintopride is a 5HT-4 antagonist with moderate 5HT-3 antagonist properties. Treatment with Lintopride significantly increases the lower oesophageal sphincter (LOS) basal tone without affecting LOS physiological relaxation after swallowing in humans. References: Goldhill J, Porquet MF, Angel I. Post-synaptic 5-HT4 receptor modulation of tachykinergic excitation of rat oesophageal tunica muscularis mucosae. Eur J Pharmacol. 1997 Apr 4;323(2-3):229-33. PubMed PMID: 9128843.
纯度:≥98%
CAS:107429-63-0