FGFR2-IN-2 (Compound 38) 是一种选择性 FGFR2 抑制剂,对 FGFR1、FGFR2 和 FGFR3 的 IC50 分别为 389、29 和 758 nM。
货号:ajcx37688
CAS:2677709-81-6
分子式:C23H22N4O
分子量:370.45
溶解度:DMSO : 62.5 mg/mL (168.71 mM; ultrasonic and warming and heat to 60°C)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
FGFR2-IN-2 (Compound 38) is a selective FGFR2 inhibitor with IC50s of 389, 29, and 758 nM for FGFR1, FGFR2, and FGFR3, respectively[1].
[1]. Lewis D Turner, et al. From Fragment to Lead: De Novo Design and Development toward a Selective FGFR2 Inhibitor. J Med Chem. 2022 Jan 27;65(2):1481-1504.