Boc-Val-Cit-PAB 是一种可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
货号:ajcx36760
CAS:870487-09-5
分子式:C23H37N5O6
分子量:479.57
溶解度:DMSO : 100 mg/mL (208.52 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Boc-Val-Cit-PAB is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.