规格: | 98% |
分子量: | 1868.07 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
Background:
SDKPDMAEIEKFDKSK is a peptide derived from thymosin β4 (Tβ4)[1].
Thymosin β4 (Tβ4) is a 43 amino acid polypeptide that belongs to a large family of highly conserved, small biologically active molecules. Thymosin β4 (Tβ4) inhibits PDGF-BB-induced fibrogenesis, proliferation and migration of HSC by blocking Akt phosphorylation[1].
[1]. Shah R, et al. Thymosin β4 inhibits PDGF-BB induced activation, proliferation, and migration of human hepatic stellate cells via its actin-binding domain. Expert Opin Biol Ther. 2018;18(sup1):177-184.