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5-hydroxy Indole-3-acetic Acid-d6
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5-hydroxy Indole-3-acetic Acid-d6图片
规格:98%
分子量:197.2
包装与价格:
包装价格(元)
500ug电议
1mg电议
5mg电议

产品介绍
An internal standard for the quantification of 5-hydroxy indole-3-acetic acid
货号:ajcx28518
CAS:2748469-82-9
分子式:C10H3D6NO3
分子量:197.2
溶解度:DMSO: soluble,Ethyl Acetate: soluble,Methanol: soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

5-hydroxy Indole-3-acetic acid-d6(5-HIAA-d6) is intended for use as an internal standard for the quantification of 5-HIAA by GC- or LC-MS. 5-HIAA is a metabolite of the monoamine neurotransmitter serotonin .1It is formed from serotoninviaa 5-hydroxy indole-3-acetaldehyde intermediate by aldehyde dehydrogenase. 5-HIAA has been used as a biomarker for the detection of neuroendocrine tumors. Brain levels of 5-HIAA are decreased in patients with severe Alzheimer's disease.2

1.Corcuff, J.-B., Chardon, L., El Hajji Ridah, I., et al.Urinary sampling for 5HIAA and metanephrines determination: Revisiting the recommendationsEndocr. Connect.6(6)R87-R98(2017) 2.Vermeiren , Y., Van Dam, D., Aerts, T., et al.Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's diseaseNeurobiol. Aging35(12)2691-2700(2014)