| 规格: | 98% |
| 分子量: | 197.2 |
| 包装 | 价格(元) |
| 500ug | 电议 |
| 1mg | 电议 |
| 5mg | 电议 |
Background:
5-hydroxy Indole-3-acetic acid-d6(5-HIAA-d6) is intended for use as an internal standard for the quantification of 5-HIAA by GC- or LC-MS. 5-HIAA is a metabolite of the monoamine neurotransmitter serotonin .1It is formed from serotoninviaa 5-hydroxy indole-3-acetaldehyde intermediate by aldehyde dehydrogenase. 5-HIAA has been used as a biomarker for the detection of neuroendocrine tumors. Brain levels of 5-HIAA are decreased in patients with severe Alzheimer's disease.2
1.Corcuff, J.-B., Chardon, L., El Hajji Ridah, I., et al.Urinary sampling for 5HIAA and metanephrines determination: Revisiting the recommendationsEndocr. Connect.6(6)R87-R98(2017) 2.Vermeiren , Y., Van Dam, D., Aerts, T., et al.Monoaminergic neurotransmitter alterations in postmortem brain regions of depressed and aggressive patients with Alzheimer's diseaseNeurobiol. Aging35(12)2691-2700(2014)
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