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Velaresol
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Velaresol图片
规格:98%
分子量:238.2
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
An Hb-O2 stabilizer
货号:ajcx28476
CAS:77858-21-0
分子式:C12H14O5
分子量:238.2
溶解度:DMF: 16 mg/mL,DMSO: 10 mg/mL,Ethanol: Slightly soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Velaresol is an oxyhemoglobin (Hb-O2) stabilizer.1It increases erythrocyte deformability in isolated human blood from a patient with sickle cell disease when used at a concentration of 1.5 mM. Velaresol (3 or 5 mM) inhibits deoxygenation-induced decreases in erythrocyte deformability in isolated human blood from a patient with sickle cell disease. It decreases oxygen tension and increases oxygen saturation of isolated human sickle erythrocytes when used at a concentration of 5 mM.2

1.Kenny, M.W., and Stuart, J.Preservation of deformability (filterability) of sickle cells by BW12C during progressive deoxygenationBr. J. Haematol.55(3)465-471(1983) 2.Gibson, J.S., Khan, A., Speake, P.F., et al.O2 dependence of K+ transport in sickle cells: The effect of different cell populations and the substituted benzaldehyde 12C79FASEB J.15(3)823-832(2001)