包装: | 1mg |
规格: | 98% |
市场价: | 239元 |
分子量: | 377.9 |
Background:
EDDP (perchlorate) (CRM) is a certified reference material that is categorized as a metabolite. It is an inactive metabolite of methadone , produced by N-demethylation in the liver, primarily by cytochrome P450 (CYP) isoform 3A4.1The activity of CYP3A4 varies widely among individuals, resulting in significantly different rates of methadone conversion to EDDP from person to person.1This product is intended for research and forensic applications.
1.Ferrari, A., Coccia, C.P., Bertolini, A., et al.Methadone--metabolism, pharmacokinetics and interactionsPharmacol.Res.50(6)551-559(2004)