An anti-allergic DHEA derivative
货号:ajcx23284
CAS:2454246-25-2
分子式:C28H36N2O5S
分子量:512.7
溶解度:Methyl Acetate: Soluble
纯度:98%
存储:Store at -20°C
库存:
现货Background:
pNPS-DHA is an arylamide derivative of docosahexaenoyl ethanolamide that has anti-allergic activity.1It inhibits degranulation of RBL-2H3 mast cells (IC50= 15 µM).pNPS-DHA (1,000 mg/kg) inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in mice.
1.Kim, I.-H., Kanayama, Y., Nishiwaki, H., et al.Structure-activity relationships of fish oil derivatives with anti-allergic activity in vitro and in vivoJ. Med. Chem.62(21)9576-9592(2019)