规格: | 98% |
分子量: | 521.9 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
Background:
C16 1-Deoxyceramide (m18:1/16:0) is a long-chain atypical ceramide containing a 1-deoxysphingosine (m18:1(4E)) backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alanine instead of serine during sphingolipid synthesis.1,2C16 1-Deoxyceramide (m18:1/16:0) has been found in RAW 264.7 cells.3
1.Steiner, R., Saied, E.M., Othman, A., et al.Elucidating the chemical structure of native 1-deoxysphingosineJ. Lipid Res.57(7)1194-1203(2016) 2.Alecu, I., Othman, A., Penno, A., et al.Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathwayJ. Lipid Res.58(1)60-71(2017) 3.JimÉnez-Rojo, N., Sot, J., Busto, J.V., et al.Biophysical properties of novel 1-deoxy-(dihydro)ceramides occurring in mammalian cellsBiophys. J.107(12)2850-2859(2014)