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9-PAHSA-d31
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
9-PAHSA-d31图片
规格:98%
分子量:570.1
包装与价格:
包装价格(元)
100ug电议
250ug电议
500ug电议
1mg电议

产品介绍
A neuropeptide with diverse biological activities
货号:ajcx21566
CAS:N/A
分子式:C34H35D31O4
分子量:570.1
溶解度:DMF: 20 mg/ml,DMSO: 15 mg/ml,Ethanol: 20 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

9-PAHSA-d31contains 31 deuterium atoms at the 2, 2', 3, 3', 4, 4', 5, 5', 6, 6', 7, 7', 8, 8', 9, 9', 10, 10', 11, 11', 12, 12', 13, 13', 14, 14', 15, 15', 16, 16, and 16 positions. It is intended for use as an internal standard for the quantification of 9-PAHSA by GC- or LC-mass spectrometry. Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity.1Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to a hydroxylated C-16 or C-18 lipid. 9-PAHSA is a FAHFA in which palmitic acid is esterified to 9-hydroxy stearic acid. PAHSAs are the most abundant forms of FAHFA in serum as well as white and brown adipose tissues of glucose tolerant AG4OX mice, which overexpress Glut4 specifically in adipose tissue.19-PAHSA is the predominant isomer of PAHSA in wild type and AG4OX mice.1It is found in humans and is reduced in the serum and adipose tissues of insulin-resistant humans.19-PAHSA improves glucose tolerance, stimulates insulin secretion, and has anti-inflammatory effects in mice.1


1.Yore, M.M., Syed, I., Moraes-Vieira, P.M., et al.Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effectsCell.159(2)318-332(2014)