规格: | 98% |
分子量: | 169.6 |
包装 | 价格(元) |
250mg | 电议 |
500mg | 电议 |
1g | 电议 |
Background:
2-Chloroadenine is a heterocyclic building block that has been used in the synthesis of adenosine antimetabolites with antineoplastic activity.1It is also the major catabolite of 2-chloro-2'-deoxyadenosine.2
1.Bauta, W.E., Schulmeier, B.E., Burke, B.J., et al.A new process for antineoplastic agent clofarabineOrg. Proc. Res. Dev.8(6)889-896(2004) 2.Bontemps, F., Delacauw, A., Cardoen, S., et al.Metabolism and cytotoxic effects of 2-chloroadenine, the major catabolite of 2-chloro-29-deoxyadenosineBiochem. Pharmacol.59(10)1237-1243(2000)