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Suc-YVAD-pNA
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Suc-YVAD-pNA图片
规格:98%
分子量:686.7
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
C31H38N6O12
货号:ajcx19628
CAS:208264-84-0
分子式:C31H38N6O12
分子量:686.7
溶解度:Acetic Acid (50%): soluble
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Suc-YVAD-pNA is a colorimetric substrate for caspase-1/interleukin-1β-converting enzyme (ICE) and caspase-4.1 Caspase-1 and caspase-4 preferentially bind to and cleave the Tyr-Val-Ala-Asp (YVAD) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of caspase-1 and caspase-4 activity.

参考文献
1. Margolin, N., Raybuck, S.A., Wilson, K.P., et al. Substrate and inhibitor specificity of interleukin-1β-converting enzyme and related caspases. J. Biol. Chem. 272(11), 7223-7228 (1997).