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Oxychlororaphine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Oxychlororaphine图片
规格:98%
分子量:223.2
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
100mg电议

产品介绍
C13H9N3O
货号:ajcx19566
CAS:550-89-0
分子式:C13H9N3O
分子量:223.2
溶解度:Soluble in DMSO
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Oxychlororaphine is a phenazine microbial metabolite that has been found in a variety of bacteria and has anticancer, antibacterial, and antifungal activities.1,2 It is cytotoxic to A549, HeLa, and SW480 cancer cells (IC50s = 32-40 μM).1 Oxychlororaphine halts the cell cycle at the G1 phase and induces apoptosis in A549 cells. It is active against Streptomyces bacteria and T. mentagrophytes, E. floccosum, C. albicans, M. audouini, and B. dermatitidis fungi when used at concentrations ranging from 12.5 to 50 ppm.2

参考文献
1. Ali, H.M., El-Shikh, M.S., Salem, M.Z.M., et al. Isolation of bioactive phenazine-1-carboxamide from the soil bacterium Pantoea agglomerans and study of its anticancer potency on different cancer cell lines. J. AOAC Int. 99(5), 1233-1239 (2016).
2. Sierra, G., and Veringa, H.A. Effect of oxy-chlororaphin on the growth in vitro of Streptomyces species and some pathogenic fungi. Nature 182(4630), 265 (1958).