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PtdIns-(3,4,5)-P3(1-stearoyl,2-docosahexaenoyl)(sodium salt)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
PtdIns-(3,4,5)-P3(1-stearoyl,2-docosahexaenoyl)(sodium salt)图片
规格:98%
分子量:1239
包装与价格:
包装价格(元)
50ug电议
100ug电议
500ug电议
1mg电议

产品介绍
Phosphatidyl inositol trisphosphate (PtdIns-(3,4,5)-P3) is a membrane phospholipid that may be cleaved by phospholipase C (PLC) to produce the second messengers inositol tetrakisphosphate (IP4) and diacylglycerol (DAG).
货号:ajcx18918
CAS:N/A
分子式:C49H82O22P4•4Na
分子量:1239
溶解度:Water: 10 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

Phosphatidyl inositol trisphosphate (PtdIns-(3,4,5)-P3) is a membrane phospholipid that may be cleaved by phospholipase C (PLC) to produce the second messengers inositol tetrakisphosphate (IP4) and diacylglycerol (DAG). IP4 triggers an increase in intracellular calcium. PtdIns-(3,4,5)-P3 (1-stearoyl, 2-docosahexaenoyl) is an uncommon phospholipid having the ω-3 fatty acid docosahexaenoate (DHA) in the sn-2 position. In addition to releasing an unusual DHA-containing DAG in response to PLC, this phospholipid can serve as a source of DHA in response to phospholipases A2 (PLA2). Importantly, the inositol head group of PtdIns-(3,4,5)-P3 can serve as an anchor for the binding of proteins bearing pleckstrin homology (PH) domains.