Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut.
货号:ajcx18806
CAS:N/A
分子式:C192H295N59O60S•XCF3COOH
分子量：4421.8
溶解度:Water: 1 mg/ml
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut. It reduces [125I]-glucagon binding to rat liver plasma membranes and a glucagon antibody in a concentration-dependent manner. Oxyntomodulin induces insulin secretion in a glucose- and concentration-dependent manner in perfused rat pancreas. It increases glucose absorption in isolated rat small intestine and enterocytes. In vivo, oxyntomodulin (25-450 pmol/kg) inhibits pentagastrin-stimulated gastric acid secretion in a dose-dependent manner in rats. It also increases plasma concentrations of insulin and glucose in Holstein cattle under normal physiological conditions.