DBCO-acid 是一种可降解 (cleavable) ADC linker,可用于合成 ADC linker DBCO-NHS ester ,及偶联物 DBCO-PEG-MMAE 。
货号:ajcx16260
CAS:1353016-70-2
分子式:C19H15NO3
分子量:305.33
溶解度:DMSO: 100 mg/mL (327.51 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
DBCO-acid is a cleavable ADC linker used in the synthesis of ADC linker DBCO-NHS ester , and drug-linker conjugates DBCO-PEG-MMAE [1].
[1]. Zimmerman ES, et al. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system. Bioconjug Chem. 2014 Feb 19;25(2):351-61.