Tos-PEG2-O-Propargyl 是一种 PROTAC linker,属于 PEG 类。Tos-PEG2-O-Propargyl 可用于合成 Thalidomide-O-PEG2-propargyl 。
货号:ajcx15720
CAS:1119249-30-7
分子式:C14H18O5S
分子量:298.35
溶解度:Ethanol: 50 mg/mL (167.59 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Tos-PEG2-O-Propargyl is a PEG-based PROTAC linker can be used in the synthesis of Thalidomide-O-PEG2-propargyl [1].
[1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.