N-deacetylatedBMS-202是BMS-202的脱乙酰基化。BMS-202是PD-l/PD-Ll相互作用的抑制剂,主要用于癌症治疗。
货号:ajcx13530
CAS:N/A
分子式:C23H27N3O2
分子量:377.48
溶解度:DMSO : ≥ 36 mg/mL (95.37 mM)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
N-deacetylated BMS-202 is the deacetylated of BMS-202. BMS-202 is an inhibitor of the PD-l/PD-Ll interaction, mainly used for cancer treatment.
BMS-202 inhibits PD-1/PD-Ll interaction, and may augment therapeutic immune response to a number of histologically distinct tumors. Blockade of the PD-1/PD-Ll ligation using antibodies to PD-Ll has been shown to restore and augment T cell activation in many systems[1].
[1]. WO2015034820 A1