IL-15-IN-1是有效,选择性的抑制剂,抑制IL-15依赖性细胞的 IC50 为0.8 μM。
货号:ajcx39294
CAS:1831830-20-6
分子式:C30H36N6O4S
分子量:576.71
溶解度:DMSO : 125 mg/mL (216.75 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
IL-15-IN-1 is a potent and selective Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells with an IC50 of 0.8 μM.
[1]. QuÉmÉner A, et al. Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization. J Med Chem. 2017 Jul 27;60(14):6249-6272.
Protocol: