Pomalidomide-C12-NH2 hydrochloride 是 PROTAC KRAS G12C degrader-1 的 E3 连接酶配体-linker 偶联物(E3 ligase ligand-linker conjugate)。PROTAC KRAS G12C degrader-1 是一种基于 Cereblon 的KRASG12C 降解剂。
货号:ajcx38898
CAS:N/A
分子式:C25H37ClN4O4
分子量:493.04
溶解度:N/A
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Pomalidomide-C12-NH2 hydrochloride is the E3 ligase ligand-linker conjugate of PROTAC KRAS G12C degrader-1 . PROTAC KRAS G12C degrader-1 is a Cereblon-based KRASG12C degrader[1].
[1]. Zeng M, et, al. Exploring Targeted Degradation Strategy for Oncogenic KRAS G12C. Cell Chem Biol. 2020 Jan 16;27(1):19-31.e6.