NLRP3/AIM2-IN-3是一种抑制NLRP3 和AIM2 炎症小体活化并具有物种差异的独特分子,其IC50值为0.077±0.008 μM。
货号:ajcx38716
CAS:1787787-60-3
分子式:C16H14N2O2
分子量:266.29
溶解度:DMSO : 250 mg/mL (938.83 mM; Need ultrasonic)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
NLRP3/AIM2-IN-3 is a unique molecule that inhibits the activation of NLRP3 and AIM2 inflammatory bodies and has species differences. Its IC 50 value is 0.077 ± 0.008 μ M。
[1]. Jiao Y, et al. Discovery of a novel and potent inhibitor with differential species-specific effects against NLRP3 and AIM2 inflammasome-dependent pyroptosis. Eur J Med Chem. 2022 Feb 11;232:114194.