CRBN modulator-1,一种 Thalidomide 类似物和 CRBN 调节剂,结合 CRBN 的IC50 值和 Ki 值分别为 3.5 μM 和 0.98 μM。
货号:ajcx33288
CAS:2407829-65-4
分子式:C17H12N2O5
分子量:324.29
溶解度:DMSO : 10 mg/mL (30.84 mM; ultrasonic and adjust pH to 2 with HCl)
纯度:98%
存储:Store at -20°C
库存:
现货Background:
CRBN modulator-1, a Thalidomide analog and a CRBN modulator extracted from WO2020006262A1, compound 10, has an IC50 of 3.5 μM and a Ki of 0.98 μM[1].
[1]. Nathanael Gray, et al. New crbn modulators. WO2020006262A1.