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β-Aminopropionitrile
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
β-Aminopropionitrile图片
包装:500mg
规格:98%
市场价:490元
分子量:70.09

产品介绍
β-Aminopropionitrile 是一种特异的不可逆赖氨酰氧化酶 (LOX) 抑制剂。β-Aminopropionitrile 靶向 LOX 或 LOXL 同工酶的活性位点。
货号:ajcx32832
CAS:151-18-8
分子式:C3H6N2
分子量:70.09
溶解度:DMSO : 130 mg/mL (1854.76 mM)|H2O : 50 mg/mL (713.37 mM)
纯度:98%
存储:Store at -20°C
库存:现货

Background:

β-Aminopropionitrile is a specific and irreversible lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile targets the active site of LOX or LOXL isoenzymes[1][2].

β-Aminopropionitrile blocks the hypoxia-induced EMT morphological and marker protein changes, and inhibited invasion and migration capacities of cervical carcinoma cells in vitro[2].


[1]. Miana M, et al. The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats. Dis Model Mech. 2015 Jun;8(6):543-51.
[2]. Yang X, et al. Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells. Oncol Rep. 2013 Feb;29(2):541-8.