Tris(2,4-di-tert-butylphenyl)phosphate是从VitexnegundoL.中分离的一种活性化合物，具有抗炎活性，并通过分子对接抑制了分泌性磷脂酶A2(sPLA2)。
货号:ajcx31616
CAS:95906-11-9
分子式:C42H63O4P
分子量：662.92
溶解度:DMSO: 2 mg/mL (3.02 mM)
纯度：98%
存储：Store at -20°C
库存：现货

Background:

Tris(2,4-di-tert-butylphenyl)phosphate is an active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A2 (sPLA2) through molecular docking[1].

Tris(2,4-di-tert-butylphenyl)phosphate (TDTBPP; 50 mg/kg and 70 mg/kg) exhibits significant anti-inflammatory activity in carrageenan induced paw odema model[1]. Tris(2,4-di-tert-butylphenyl)phosphate (50 mg/kg and 70 mg/kg) reduces the raw paw odema volume significantly[1].

[1]. Vinuchakkaravarthy T, et al. Active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory Phospholipase A(2) through molecular docking. Bioinformation. 2011;7(4):199-206.