Nomegestrol 是一种有效的口服孕激素,作为选择性全孕酮受体激动剂,对大鼠子宫孕酮受体的 Kd 为 5.44 nM,具有中等的抗雄激素活性和强的抗雌激素活性。
货号:ajcx28552
CAS:58691-88-6
分子式:C21H28O3
分子量:328.5
溶解度:Chloroform: soluble,DMSO: slightly soluble,Methanol: slightly soluble
纯度:98%
存储:Store at -20°C
库存:
现货Background:
Nomegestrol is a derivative of 19-norprogesterone.1It increases nuclear levels of the progesterone receptor in rat uterus when administered at a dose of 1 mg/animal.
1.Botella, J., Duc, I., Delansorne, R., et al.Structure-activity and structure-affinity relationships of 19-nor-progesterone derivatives in rat uterusJ. Endocrinol. Invest.13(11)905-910(1990)