Mavoglurant (AFQ-056; AFQ056) is a potent and non-competitive mGlu5 (metabotropic glutamate receptor 5) receptor antagonist (IC50=30 nM) with the potential to be used for treatment of fragile X syndrome. It showed efficacy in the treatment of L-dopa induced dyskinesias in
Parkinson's disease and Fragile X mental retardation in proof of
principle studies.
纯度:≥98%
CAS:543906-09-8