NSC 636819 是 KDM4A/KDM4B 的竞争性和选择性抑制剂。 KDM4A/KDM4B 是前列腺癌的潜在进展因素。 NSC 636819 具有研究癌症疾病，尤其是前列腺癌的潜力。
货号:ajcx26990
CAS:1618672-71-1
分子式:C22H12Cl4N2O4
分子量：510.15
溶解度:Soluble in DMSO
纯度：98%
存储：Store at -20°C
库存：现货

Background:

KDM4A/KDM4B inhibitor; inhibits histone demethylase activity on H3K9me3 and induces apoptosis in LNCaP prostate cancer cells in vitro. Also negatively regulates androgen-responsive genes.

Chu et al (2014) KDM4B as a target for prostate cancer: structural analysis and selective inhibition by a novel inhibitor. J.Med.Chem. 57 5975 PMID:24971742