ACT-373898 是 Macitentan 的一种无活性羧酸代谢物。
货号:ajcx25768
CAS:1433875-14-9
分子式:C15H17BrN4O5S
分子量：445.3
溶解度:DMSO: soluble,Ethanol: soluble
纯度：98%
存储：Store at -20°C
库存：现货

Background:

ACT-373898 is a metabolite of the endothelin (ET) receptor type A (ET_A) and ET_Bdual antagonist macitentan .¹

1.Dingemanse, J., Sidharta, P.N., Maddrey, W.C., et al.Efficacy, safety and clinical pharmacology of macitentan in comparison to other endothelin receptor antagonists in the treatment of pulmonary arterial hypertensionExpert Opin. Drug Saf.13(3)391-405(2013)