您好,欢迎来到化工原料网! [登录] [免费注册]
化工原料网
位置:首页 > 产品库 > 7-Methoxy-4-(trifluoromethyl)coumarin
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
7-Methoxy-4-(trifluoromethyl)coumarin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
7-Methoxy-4-(trifluoromethyl)coumarin图片
规格:98%
分子量:244.2
包装与价格:
包装价格(元)
50mg电议
100mg电议
250mg电议

产品介绍
A fluorogenic substrate for CYPs
货号:ajcx25462
CAS:575-04-2
分子式:C11H7F3O3
分子量:244.2
溶解度:DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:2): 0.3 mg/ml,DMSO: 25 mg/ml,Ethanol: 10 mg/ml
纯度:98%
存储:Store at -20°C
库存:现货

Background:

7-Methoxy-4-(trifluoromethyl)coumarin is a fluorogenic substrate for cytochrome P450s (CYPs).1Upon enzymatic cleavage by CYPs, 7-hydroxy-4-(trifluoromethyl)coumarin (HFC) is released and its fluorescence can be used to quantify CYP activity. HFC displays excitation/emission maxima of 410/510 nm, respectively.


1.Donato, M.T., JimÉnez, N., Castell, J.V., et al.Fluorescence-based assays for screening nine cytochrome P450 (P450) activities in intact cells expressing individual human P450 enzymesDrug Metab. Dispos.32(7)699-706(2004)