靶标：
CCR3
产品别名：
C C CKR3； CC-CKR-3； CD193； CKR 3； CKR3； CMKBR3； CCR3； C-C motif chemokine receptor 3； C-C motif chemokine receptor 3； C-C chemokine receptor type 3； C-C CKR-3； CC chemokine receptor 3； CCR-3； b-chemokine receptor； chemokine (C-C motif) receptor 3； eosinophil CC chemokine receptor 3； eosinophil eotaxin receptor； 细胞表面趋化因子受体3； 趋化因子C-C-基元受体3(CCR3)；
背景信息：
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009],
宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。
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