ML399 is an inhibitor of the menin--MLL interaction. It acts by demonstrating strong and selective effects in MLL leukemia cells and validating specific mechanism of action. References: Senter T, Gogliotti RD, Han C, Locuson CW, Morrison R, Daniels JS, Cierpicki T, Grembecka J, Lindsley CW, Stauffer SR. Progress towards small molecule menin-mixed lineage leukemia (MLL) interaction inhibitors with in vivo utility. Bioorg Med Chem Lett. 2015 Jul 1;25(13):2720-5. doi: 10.1016/j.bmcl.2015.04.026. Epub 2015 Apr 25. PubMed PMID: 25987377.
纯度:≥98%
CAS:1560968-49-1