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5-三磷酸肌醇受体3抗体
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。

产品名称
Anti-ITPR3
Anti-inositol 1,4,5-trisphosphate receptor type 3 Antibody
产品介绍
靶标:

ITPR3


产品别名:

IP3R; IP3R3; ITPR3; inositol 1,4,5-trisphosphate receptor type 3; inositol 1,4,5-trisphosphate receptor type 3; inositol 1,4,5-trisphosphate receptor type 3; IP3 receptor; inositol 1,4,5-triphosphate receptor, type 3; insP3R3; type 3 InsP3 receptor; 5-三磷酸肌醇受体3;


背景信息:
ITPR3 encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth. ITP3 channels serve an important role in the taste transduction pathway of sweet, bitter and umami tastes the gustatory system. ITP3 channels allow the flow of Calcium out of the endoplasmic reticulum in response to IP3. Calcium cations result in the activation of TRPM5 which leads to a depolarisation generating potential and an action potential.

宿主:Rbt
类型:Pab
同种型:IgG  
应用:WB
纯化方式:亲和纯化
偶联物:Unconjugated
性状:液体
存储溶液:参阅说明书
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user           
储存:经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。