Smad同源物7(Smad7)抗体

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Smad同源物7(Smad7)抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

细胞信号转导分子SMAD7抗体
Anti-SMAD7

产品介绍

靶标：

SMAD7

产品别名：

CRCS3； MADH7； MADH8； SMAD7； SMAD family member 7； SMAD family member 7； mothers against decapentaplegic homolog 7； MAD (mothers against decapentaplegic, Drosophila) homolog 7； MAD homolog 8； Mothers against decapentaplegic, drosophila, homolog of, 7； SMAD, mothers against DPP homolog 7； hSMAD7； mothers against DPP homolog 8； Smad同源物7(Smad7)；细胞信号转导分子SMAD7；

背景信息：

The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010],

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。