Ro 60-0175 fumarate is a potent and selective SR-2 agonist. It shows selectivity for the 5-HT2C subtype (pKis are 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively). References: Lagière M, Navailles S, Mignon L, Roumegous A, Chesselet MF, De Deurwaerdère P. The enhanced oral response to the 5-HT2 agonist Ro 60-0175 in parkinsonian rats involves the entopeduncular nucleus: electrophysiological correlates. Exp Brain Res. 2013 Oct;230(4):513-24. doi: 10.1007/s00221-013-3478-4. Epub 2013 Mar 28. PubMed PMID: 23535834.

纯度：≥98%

CAS：169675-09-6