Leucyl-phenylalanine amide is an intermediate in the synthesis of γ-Secretase Inhibitor, the enzyme complex that catalyzes the cleavage of the amyloid precursor protein (APP) to generate amyloid β-peptide (Aβ), the major causative agent in Alzheimer disease (AD). References: Peyton D, Breslow E. Use of perdeuterated peptides in NMR studies of neurophysin-hormone interaction: demonstration of peptide-specific changes in neurophysin resonances. Biochem Biophys Res Commun. 1985 May 16;128(3):1211-8. PubMed PMID: 4004858.
纯度:≥98%
CAS:38678-60-3