Fas相关磷酸酶1抗体

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Fas相关磷酸酶1抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

非受体型蛋白酪氨酸磷酸酶13(PTPN13)抗体
Anti-PTPN13

产品介绍

靶标：

PTPN13

产品别名：

FAP-1； PNP1； PTP-BAS； PTP-BL； PTP1E； PTPL1； PTPLE； hPTP1E； PTPN13； protein tyrosine phosphatase non-receptor type 13； protein tyrosine phosphatase non-receptor type 13； tyrosine-protein phosphatase non-receptor type 13； fas-associated protein-tyrosine phosphatase 1； hPTPE1； protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)； protein-tyrosine phosphatase 1E； protein-tyrosine phosphatase PTPL1； Fas相关磷酸酶1；非受体型蛋白酪氨酸磷酸酶13(PTPN13)；

背景信息：

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, ha

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。