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K02288
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
K02288图片
CAS NO:1431985-92-0
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
10mM * 1mL in DMSO电议

产品名称
K 02288, K-02288
产品介绍

生物活性

K02288是一种有效的选择性I型BMP受体抑制剂,对ALK2,ALK1和ALK6的IC50为1.1、1.8、6.4 nM。

Targets

TargetValue
ALK2IC50: 1.1nM
ALK1IC50: 1.8nM
ALK6IC50: 6.4nM
ALK3IC50: 34.4nM
ALK4IC50: 302nM
ALK5IC50: 321nM

化学数据

目录号A14311
作用机制Inhibitor (抑制剂)
M. Wt352.38
FormulaC20H20N2O4
Purity>99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for36 months.
In solution, store at -20ºC and use within3 monthsto prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No.1431985-92-0
SynonymsK 02288, K-02288
SMILESCOC1=CC(=CC(=C1OC)OC)C2=C(N=CC(=C2)C3=CC(=CC=C3)O)N

溶解度

In vitroDMSO67 mg/mL (190.13 mM)
WaterInsoluble
EthanolInsoluble
*<1 mg/ml means slightly soluble or insoluble.
*Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

储备液配制

Concentration / Solvent Volume / Mass1 mg5 mg10 mg
0.1 mM28.38 mL141.89 mL283.78 mL
0.5 mM5.68 mL28.38 mL56.76 mL
1 mM2.84 mL14.19 mL28.38 mL
5 mM0.57 mL2.84 mL5.68 mL

*The above data is based on the productmolecular weight 352.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.