RS-504393 is a potent and highly selective CCR2 chemokine receptor antagonist with IC50s of 98 nM and > 100 μM for inhibition of human recombinant CCR2b and CCR1 receptors respectively. It inhibits MCP-1 chemotaxis (IC50 = 330 nM) and ischemia-reperfusion injury in kidneys.
纯度:≥98%
CAS:300816-15-3