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Laniquidar
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:197509-46-9
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

Laniquidar is a third-generation P-gp inhibitor, which has been used in clinic trials for modulating multidrug resistance transporters. A study of docetaxel in combination with the new orally administered P-glycoprotein (P-gp) inhibitor R101933 showed that this combination was feasible. However, due to the low orally bioavailable bioavailability of R101933 and high interpatient variability, no further attempts to increase the level of P-gp inhibition were made. References: Moerman L, Dumolyn C, Boon P, De Vos F. The influence of mass of [11C]-laniquidar and [11C]-N-desmethyl-loperamide on P-glycoprotein blockage at the blood-brain barrier. Nucl Med Biol. 2012 Jan;39(1):121-5. Epub 2011 Sep 29. PubMed PMID: 21958857.

纯度:≥98%

CAS:197509-46-9