Langkamide is a HIF-2 inhibitor, which showed HIF-2 inhibitory activity with EC50 of 14.0 uM. Langkamide may be used fortargeting HIFs mediated regulation of CSCs. References: Bokesch HR, Gardella RS, Rabe DC, Bottaro DP, Linehan WM, McMahon JB, McKee
TC. A new hypoxia inducible factor-2 inhibitory pyrrolinone alkaloid from roots
and stems of Piper sarmentosum. Chem Pharm Bull (Tokyo). 2011;59(9):1178-9.
PubMed PMID: 21881266; PubMed Central PMCID: PMC3166232.
纯度:≥98%
CAS:1370510-16-9