L-822179 or α5IA is a selective inverse agonist for Α5 subtype of GABAA receptor with a higher intrinsic activity at the A5 subtype than other drugs. α5IA enhances cognition in laboratory animals without being proconvulsant or anxiogenic. α5IA acts as an "alcohol antagonist," markedly reducing the amnesic effect of alcohol and partially attenuating sedation, similar to Ro15-4513, but without the anxiogenic effect. α5IA offers promise as a tool to study cognitive disorders, memory function, and treatment of alcohol-related disorders. References: Lesaffre E. Noninferiority Clinical Trials: The Good, the Bad, and the Ugly. Semin Liver Dis. 2018 May;38(2):97-102. doi: 10.1055/s-0038-1655777. Epub 2018 Jun 5. PubMed PMID: 29871016.

纯度：≥98%

CAS：215874-86-5