SLCO1B3抗体

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SLCO1B3抗体

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

产品名称

Anti-SLCO1B3
Anti-solute carrier organic anion transporter family member 1B3 Antibody

产品介绍

靶标：

SLCO1B3

产品别名：

HBLRR； LST-2； LST-3TM13； LST3； OATP-8； OATP1B3； OATP8； SLC21A8； SLCO1B3； solute carrier organic anion transporter family member 1B3； solute carrier organic anion transporter family member 1B3； solute carrier organic anion transporter family member 1B3； liver-specific organic anion transporter 2； liver-specific organic anion transporter 3TM13； organic anion transporter 8； organic anion transporter LST-3c； organic anion-transporting polypeptide 8； solute carrier family 21 (organic anion transporter), member 8；

背景信息：

OATP1B3, which is encoded by the gene SLCO1B3, is a member of the OATP (organic anion transporting polypeptide) superfamily. SLCO1B3 is a functional transporter normally expressed in the liver, and responsible for transporting a variety of endogenous and exogenous compounds, including hormones and their conjugates as well as some anticancer drugs. SLCO1B3 is an influx transporter located at the hepatocyte basolateral membrane and it is involved in the uptake of a broad range of drug substrates including docetaxel. OATP1B3 expression is limited to the liver in healthy tissues, but the extrahepatic expression of SLCO1B3 has been detected in different cancer cell lines and cancer tissues. Both SLCO1B3 and SLCO1B1 are located on chromosome 12 encompassing the gene locus SLCO1B7.

宿主：Rbt
类型：Pab
同种型:IgG
应用：WB
纯化方式：亲和纯化
偶联物：Unconjugated
性状：液体
存储溶液：参阅说明书
浓度：Batch dependent (Please refer to the vial label for the specific concentration.)
稀释比例: Optimal dilutions/concentrations should be determined by the end user
储存：经常使用则4°C保存。-20°C保存不超过两年。避免反复冻融。
注意事项：仅供实验室使用。不适用于人类或动物的任何临床，治疗或诊断用途。不适合动物或人类食用。