S3QEL-2 is a modulator of the retrograde signaling. It acts by strongly mitigating the oxidative stress-induced apoptosis that limits the yield of functional ss-cells from intact islets. References: Orr AL, Vargas L, Turk CN, Baaten JE, Matzen JT, Dardov VJ, Attle SJ, Li J, Quackenbush DC, Goncalves RL, Perevoshchikova IV, Petrassi HM, Meeusen SL, Ainscow EK, Brand MD. Suppressors of superoxide production from mitochondrial complex III. Nat Chem Biol. 2015 Nov;11(11):834-6. doi: 10.1038/nchembio.1910. Epub 2015 Sep 14. PubMed PMID: 26368590; PubMed Central PMCID: PMC4618194.
纯度:≥98%
CAS:890888-12-7