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L67
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:325970-71-6
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

L67 is a DNA Ligase Inhibitor. L67 inhibited DNA ligases I and III. L67 is a simple competitive inhibitor with respect to nicked DNA. L67 inhibits DNA ligases I and III with IC50 of 10 μM and 10 μM.). L67 significantly increased the cytotoxicity of DNA-damaging. References: Chen X, Zhong S, Zhu X, Dziegielewska B, Ellenberger T, Wilson GM, MacKerell AD Jr, Tomkinson AE. Rational design of human DNA ligase inhibitors that target cellular DNA replication and repair. Cancer Res. 2008 May 1;68(9):3169-77. doi: 10.1158/0008-5472.CAN-07-6636. PubMed PMID: 18451142; PubMed Central PMCID: PMC2734474.

纯度:≥98%

CAS:325970-71-6