Description: L-692429 HCl is a new, potent nonpeptidyl growth hormone secretagogue (GHS) acting as an agonist of GHS with a Ki of 63 nM for binding to the GPCR.
References:
[1]. Inhibition of L-692,429-stimulated rat growth hormone release by a weak substance P antagonist: L-756,867. J Endocrinol. 1997 Jan;152(1):155-8.
[2]. Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling. Mol Endocrinol. 2005 Sep;19(9):2400-11.
Related CAS #: 145455-23-8 (free base) 169188-19-6 (HCl) 145455-80-7 (TFA)