QARS1 (Glutaminyl-TRNA Synthetase 1) is a Protein Coding gene. The QARS1 gene, located on 3p21.31, is conserved in chimpanzee, Rhesus monkey, dog, cow, and rat, etc. An important paralog of this gene is EPRS1. QARS1 is widely expressed in the colon, skin, and other tissues. QARS1 deficiency has been described to be a cause of a neurodegenerative disorder associated with severe developmental delay, microcephaly, delayed myelination, and intractable epilepsy. Epilepsy is thought to be more severe than other tRNA synthetase disorders. Among its related pathways are tRNA Aminoacylation and Viral mRNA Translation.239 organisms have orthologs with human gene QARS1.