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Tripelennamine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:91-81-6
规格:≥98%
包装与价格:
包装价格(元)
5g电议
10g电议
25g电议
50g电议

产品介绍

Description: Tripelennamine (Pyribenzamine) is a potent and widely used H1 receptor antagonist and a an antipruritic agent, inhibiting PhIP glucuronidation with IC50 of 30 μM. Tripelennamine is a substrate for a tertiary amine UDP-glucuronosyltransferases which catalyzes the formation of quaternary ammonium-linked glucuronides. Tripelennamine inhibits the glucuronidation of 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine (PhIP) by a mixture of competitive and noncompetitive inhibition in both human and rabbit liver microsomes.

References: Chem Res Toxicol. 1993 Nov-Dec;6(6):846-51; J Appl Physiol (1985). 2002 Apr;92(4):1515-23.

Related CAS #: 154-69-8 (HCl) 91-81-6 (free base)

纯度:≥98%

CAS:91-81-6